NEONATAL PLASMA POLARIZES TLR4-MEDIATED CYTOKINE RESPONSES TOWARDS LOW IL-12P70 AND HIGH IL-10 PRODUCTION VIA DISTINCT FACTORS.

Neonatal plasma polarizes TLR4-mediated cytokine responses towards low IL-12p70 and high IL-10 production via distinct factors.

ALOE Human neonates are highly susceptible to infection, which may be due in part to impaired innate immune function.Neonatal Toll-like receptor (TLR) responses are biased against the generation of pro-inflammatory/Th1-polarizing cytokines, yet the underlying mechanisms are incompletely defined.Here, we demonstrate that neonatal plasma polarizes TL

read more


Decolonising national evaluation systems

Background: The world is facing rapidly declining health of the climate and ecosystems ALOE on which all species depend, with wealth accumulating in the hands of a few, a result of unsustainable economic systems.Evaluation has the potential for a significant role in learning from the past and helping to guide a regenerative future, but for this, th

read more

Static and dynamic tests of pear bruise sensitivity

The paper is a continuation of the preceding research of bruising sensitivity applied to different pear varieties.This study was based on quasi-static fruit testing in compression between two plates.One part of the method is based on determining the hysteresis losses corresponding to the predetermined low level bruising.This paper contains an attem

read more